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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC6
All Species:
26.67
Human Site:
T272
Identified Species:
45.13
UniProt:
Q99741
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99741
NP_001245.1
560
62720
T272
R
K
L
E
K
H
M
T
A
E
K
G
P
M
I
Chimpanzee
Pan troglodytes
XP_001170406
560
62717
T272
R
K
L
E
K
H
M
T
A
E
K
G
P
M
I
Rhesus Macaque
Macaca mulatta
XP_001096756
559
62520
T272
R
K
L
E
K
H
M
T
A
D
K
G
P
M
I
Dog
Lupus familis
XP_537648
559
62507
T271
K
K
L
E
N
H
M
T
A
E
K
G
P
M
I
Cat
Felis silvestris
Mouse
Mus musculus
O89033
562
62595
T274
R
K
L
E
K
H
L
T
A
E
K
G
P
M
I
Rat
Rattus norvegicus
NP_001101768
561
62295
T273
R
K
L
E
K
H
L
T
A
E
R
G
P
M
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519126
361
39672
R107
E
R
G
H
P
S
E
R
E
D
V
R
V
G
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001081844
554
60731
T265
R
N
L
E
K
L
V
T
S
K
G
P
I
I
L
Zebra Danio
Brachydanio rerio
NP_001120805
561
61262
S284
L
E
K
Y
L
T
S
S
G
P
T
V
L
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648247
662
75116
K365
E
A
I
Q
R
H
L
K
T
A
K
R
M
L
L
Honey Bee
Apis mellifera
XP_625142
549
62089
I262
V
V
I
E
K
Y
L
I
S
N
H
K
M
L
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999666
582
64455
A266
K
A
L
Q
K
A
F
A
S
N
G
P
T
V
L
Poplar Tree
Populus trichocarpa
XP_002299817
498
55546
L244
I
A
D
E
L
D
Y
L
I
T
K
D
R
A
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P09119
513
58018
I259
P
T
V
S
F
V
L
I
G
M
A
N
S
L
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96
89.1
N.A.
79.5
80
N.A.
45.3
N.A.
63.7
49
N.A.
33.9
36
N.A.
40
Protein Similarity:
100
100
97.5
93.5
N.A.
87.3
88.9
N.A.
52.8
N.A.
77.5
67.3
N.A.
52.1
57.3
N.A.
58.5
P-Site Identity:
100
100
93.3
86.6
N.A.
93.3
86.6
N.A.
0
N.A.
33.3
0
N.A.
13.3
13.3
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
20
N.A.
66.6
26.6
N.A.
53.3
53.3
N.A.
46.6
Percent
Protein Identity:
25.8
N.A.
N.A.
N.A.
20.1
N.A.
Protein Similarity:
46.4
N.A.
N.A.
N.A.
41.2
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
22
0
0
0
8
0
8
43
8
8
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
8
0
0
0
15
0
8
0
0
8
% D
% Glu:
15
8
0
65
0
0
8
0
8
36
0
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
15
0
15
43
0
8
0
% G
% His:
0
0
0
8
0
50
0
0
0
0
8
0
0
0
0
% H
% Ile:
8
0
15
0
0
0
0
15
8
0
0
0
8
8
43
% I
% Lys:
15
43
8
0
58
0
0
8
0
8
50
8
0
0
0
% K
% Leu:
8
0
58
0
15
8
36
8
0
0
0
0
8
29
36
% L
% Met:
0
0
0
0
0
0
29
0
0
8
0
0
15
43
0
% M
% Asn:
0
8
0
0
8
0
0
0
0
15
0
8
0
0
0
% N
% Pro:
8
0
0
0
8
0
0
0
0
8
0
15
43
0
0
% P
% Gln:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
43
8
0
0
8
0
0
8
0
0
8
15
8
0
0
% R
% Ser:
0
0
0
8
0
8
8
8
22
0
0
0
8
0
0
% S
% Thr:
0
8
0
0
0
8
0
50
8
8
8
0
8
0
0
% T
% Val:
8
8
8
0
0
8
8
0
0
0
8
8
8
8
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
8
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _